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Effect of Contralateral Occlusion on Long-Term Efficacy of Endarterectomy in the Asymptomatic Carotid Atherosclerosis Study (ACAS) Stroke 31:2330-2334, Baker,W.H.,et al, 2000 See this aricle in Pubmed Article Abstract For those without contralateral occlusion, surgery was associated with a 6.7% absolute reduction in the 5-year risk (95% CI, 2.1% to 11.4%), while for those with a contralateral occlusion, surgery was associated with a 2.0% absolute increase in risk (95% CI, -9.3% to 5.2%), which was a statistically significant difference in the effect of surgery (P=0.047). This difference is primarily attributable to low long-term risk for medically managed patients with contralateral occlusion. While thi s post hoc analysis should be interpreted with caution, the findings suggest that endarterectomy in asymptomatic subjects with contralateral occlusion provides no long-term benefit (an may be harmful) in preventing stroke and death. These findings were a result of the benign course of medically treated subjects.

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(click to filter results - removes previous filter) carotid artery disease carotid artery disease,asymptomatic carotid artery occlusion,neck carotid artery stenosis,contralateral occlusion with cerebrovascular accident,prevention of efficacy endarterectomy,carotid endarterectomy,carotid-contralateral carotid occlusion-stenosis endarterectomy,carotid-long term results prevention of neurologic disorders

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